夕頭

News ~2021

^Interactions of OSW-1 with lipid bilayers in comparison with digitonin and soyasaponin ̄ has been published in Chemical and Pharmaceutical Bulletin

^Phospholipid-dependent functions of a macrocyclic analogue of the ion-channel-forming antibiotic Gramicidin A ̄ has been published in Chemical and Pharmaceutical Bulletin.

^Computational and experimental analysis on the conformational preferences of anticancer saponin OSW-1 ̄ has been accepted in The Journal of Organic Chemistry.

Yushi visited Can Tho University in Can Tho City, VietNam through the Visionary Program for Science Students at TUAT.

Prof. Micha Fridman has stayed with us at TUAT as the GIR visiting professor and gave a Departmental Seminar on 19 Nov, 2019.

^Phospholipid-dependent functions of a macrocyclic analogue of the ion-channel-forming antibiotic gramicidin A ̄ has been accepted in Chemical and Pharmaceutical Bulletin.

Kanna presented a poster at the research poster session at TUAT Open Campus.

"Clickable gold nanoparticles for streamlining capture, enrichment and release of alkyne-labelled proteins" has been published in Bioorganic and Medical Chemistry Letters.

Prof. Bengang Xing has visited us at TUAT to give the Departmental Seminar on 1 Oct at TUAT.

^Development of chemical probes for functional analysis of anticancer saponin OSW-1 ̄ has been published in The Chemical Record. This paper has been highlighted as the cover picture article.

Naoko and Kanna presented posters at the 2nd Australasian Glycoscience Symposium/HUPO2019 at Adelaide, Australia.

仝滅i冩梢におけるクラウドファンディング坤ラウドファンディングで冩梢Mを@誼するための滅i冩梢テ`マ々をテ`マとしたグル`プhでは、 儲さんのチ`ムが戞‡和埴のチ`ムが3了に秘pしました。 Nanako and Shione attended 2019 TIAnano Bio Summer School at Ochanomizu University. Nanako's team won first prize and Shione's third place in a competition to design a glycoscience research project.

Summer internship was held for freshman students at the Dept. of Biotechnology and Life Science.

Nanako Suto and Kanna Mori presented posters at the 14th annual meeting of the Japanese Society for Chemical Biology.

Nanako Suto presented a poster at the 18th Seminar of the Japanese Association for the Pursuit of New Bioactive Resources.

"Anticancer saponin OSW-1 is a novel class of selective Golgi stress inducer ̄ has been published in Bioorganic and Medicinal Chemistry Letters.

Nanako Suto and Kanna Mori presented their works at the 99th annual meeting of the Chemical Society of Japan at Konan University.

Rina Komatsu presented a poster at Glyco TOKYO2018 at RIKEN.

" Target Identification of Yaku'amide B and its two distinct activities against mitochondrial F0F1-ATP synthase " has been published in Journal of the American Chemical Society.

" Design and synthesis of small molecule-conjugated photoaffinity nanoprobes for a streamlined analysis of binding protein " has been published in Bioorganic and Medicinal Chemistry Letters.

Rina Komatsu gave an oral presentation at JSPS Asian Chemical Probe Reserch Hub, 2nd A3 Young Scientist Meeting in Sendai.

"Synthesis of alkyne-tagged and biotin-tagged Sortin1 as novel photoaffinity probes."

Rina Komatsu presented a poster at The Society of Japanese Women Scientists.

Takumi Umezawa, Ikuho Kaneda, and Naohiro Kobayashi presented posters at The 7th CSJ Chemistry Festa 2017.

Rina Komatsu presented a poster at The 26th French-Japanese Symposium on Medicinal and Fine Chemistry.

Naho Isogai has started as a visiting student in the Dr. Xiang David Li group at University of Hong Kong.

Naho Isogai and Rina Komatsu presented posters at the 52th Natural Product Chemistry Symposium in Shizuoka.

Naho Isogai and Rina Komatsu presented posters at the 12th Annual Meeting of Japanese Society for Chemical Biology in Hokkaido.

"Dissecting the structural basis for the intracellular delivery of OSW-1 by fluorescent probes."

Naho Isogai, Amane Kato and Tadashi Hattori presented their works at the 97th annual meeting of the Chemical Society of Japan at Keio University.

"Synthesis of a Fluorescent Photoaffinity Probe of OSW-1 bi Site-Selective Acylation of an Inactive Congener and Biological Evaluation" has been published in a themed issue entitled "Site-Selective molecular transformations" in Chemical Communications. This paper has been highlighted as a back cover.

Takeshi Iida presented a poster at GlycoTOKYO2016 at Tokyo Institute of Technology.

Rina Komatsu has started as a visiting student in the Zubarev group at Karolinska Institute.

"Design and synthesis of fluorescent glycolipid photoaffinity probes and their photoreactivity" has been accepted in Bioorganic and Medicinal Chemistry letters.

Naho Isogai and Amane Kato presented posters at the 51th Natural Product Chemistry Symposium in Niigata.

Rina Komatsu gave an oral presentation at 71th The Society of Synthetic Organic Chemistry, Japan Kanto branch symposium in Tokyo.

Sho Narita and Amane Kato presented a poster at 96th CSJ in Kyoto.

"Two-step synthesis of a clickable photoaffinity probe from an anticancer saponin OSW-1 and its photochemical reactivity" has been accepted in Asian Journal of Organic Chemistry.

Rika Yamada presented a poster at Pacifichem 2015 in Hawaii, U.S.A.

Tomoya Takeshita and Tamayo Yamaguchi presented at 33rd Medicinal Chemistry Symposium in Makuhari.

Sakae Mizuno has started as a visiting student in the Kawamura Group at the Department of Chemistry, Hunter College in New York, U.S.A..

"Gold Nanoparticle-Based Multivalent Carbohydrate Probes : Selective Photoaffinity Labeling of Carbohydrate-Binding Proteins" has been published in Chemical Science.