- 2025
- Ibban SS, Naima J, Kato R, Kuroda T, and Ohta Y
"Antioxidant Effects of Exogenous Mitochondria: The Role of Outer
Membrane Integrity"
Antioxidants, 14, 951, database
Okutani A, Naima J, Ogihara A, Motoichi T, Ohsawa I, and Ohta Y
"A method for isolating and cryopreserving intact mitochondria with
improved integrity and functionality"
Biophysics and Physicobiology 22, e220012, database
- 2024
- Naima J, and Ohta Y
"Potassium Ions Decrease Mitochondrial Matrix pH: Implications for
ATP Production and Reactive Oxygen Species Generation"
Int. J. Mol. Sci. 25, 1233, database
- 2022
- Aklima J, Onchaiya S, Saotome T, Velmurgan P, Motoichi T, Naima J, Kuroda Y, and Ohta Y
"Direct Analysis of Mitochondrial Damage Caused by Misfolded/Destabilized
Proteins"
Int. J. Mol. Sci. 23, 9881, database
Cui M, Takahashi M, Chen Y, Liu B, Ohta Y, and Miyake T
"pH modulation in adhesive cells with a protonic biotransducer”
Bioelectrochemistry 147, 108202, database
Yoneda M, Aklima J, Ohsawa I, and Ohta Y
"Effects of proton pumping on the structural rigidity of cristae in
mitochondria"
Arch. Biochem. Biophys. 720, 109172, database
- 2021
- Aklima J, Onojima T, Kimura S, Umiuchi K, Shibata T, Kuraoka Y, Oie Y,
Suganuma Y and Ohta Y
"Effects of Matrix pH on Spontaneous Transient Depolarization and
Reactive Oxygen Species Production in Mitochondria"
Front. Cell Dev. Biol. 9, 692776, database
- 2019
- Shibata T, Yoneda M, Morikawa D, and Ohta Y
"Time-lapse imaging of Ca2+-induced swelling and permeability transition: Single mitochondrion study"
Arch. Biochem. Biophys. 663, 288-296, database
- 2018
- Zhang Z, Kashiwagi H, Kimura S, Kong S, Ohta Y, and Miyake T
"A protonic biotransducer controlling mitochondrial ATP synthesis"
Sci. Rep. 8, 10423, database
Kanazashi Y, Takara N, Iwami K, Ohta Y, and Umeda N
"Evaluation of mitochondrial activity by two-photon absorption with
near-field multioptical fiber probes"
Jpn. J. Appl. Phys. 57, 046601, database
- 2017
- Hirusaki K. Yokoyama K, Cho K, and Ohta Y
"Temporal depolarization of mitochondria during M phase"
Sci. Rep. 7, 16044, database
Hiraizumi M, Komatsu R, Shibata T, Ohta Y, and Sakurai K
"Dissecting the structural basis for the intracellular delivery of
OSW-1 by fluorescent probes"
Organic & Biomol. Chem. 15, 3568-3670, database
Sakurai K, Hiraizumi M, Isogai N, Komatsu R, Shibata T, and Ohta Y
"Synthesis of a fluorescent photoaffinity probe of OSW-1 by site-selective
acylation of an inactive congener and biological evaluation"
Chem. Commun. 53, 517-520, database
Shinohe D, Kobayashi A, Gotoh M, Tanaka K, and Ohta Y
"Long-term inhibition of cyclophilin D results in intracellular translocation
of calcein AM from mitochondria to lysosomes"
Arch. Biochem. Biophys. 613, 53-60, database
- 2016
- Shi X, Osaki H, Matsunomoto Y, Fujita C, Shinohe D, Ashida N, Choi H, and
Ohta Y
"Partial contribution of mitochondrial permeability transition to
t-butyl hydroperoxide-induced cell death”
Biochem. Biophys. Reports 7, 33-38, database
- 2015
- Li Y, Honda S, Iwami K, Ohta Y, and Umeda N
"Analysis of mitochondrial mechanical dynamics using a confocal fluorescence
microscope with a bent optical fibre”
Journal of Microscopy 260, 140-51, database
Shibata T, Yamashita S, Hirusaki K, Katoh K, and Ohta Y
"Isolation of mitochondria by gentle cell membrane disruption, and
their subsequent characterization"
Biochem. Biophys. Res. Commun. 463, 563-8, database
Haseda K, Kanematsu K, Noguchi K, Saito H, Umeda N, and Ohta Y
"Significant correlation between refractive index and activity of
mitochondria: Single Mitochondrion Study"
Biomedical Optics Express 6, 859-69, database
- 2014
- Sohya S, Kamioka T, Fujita C, Ishihara K, Maki T, Ohta Y, and Kuroda Y
"Biochemical and biophysical characterization of an unexpected bacteriolysis activity of VanX, a member of the vancomycin-resistance vanA gene cluster"
J.Biol.Chem. 289, 35686-35694, database
Morikawa D, Kanematsu K, Shibata T, Haseda K, Umeda N, and Ohta Y
"Detection of swelling of single isolated mitochondrion with optical
microscopy"
Biomedical Optics Express 5, 848-857, database
Yamada R, Takeshita T, Hiraizumi M, Shinohe D, Ohta Y, and Sakurai K
"Fluorescent analog of OSW-1 and its cellular localization"
Bioorg. Med. Chem. Lett. 24, 1839-42, database
- 2012
- Kanazashi Y, Li Y, Onojima T, Iwami K, Ohta Y, and Umeda N
"pH Measurement Using Dual-Wavelength Fluorescent Ratio by Two-Photon
Excitation for Mitochondrial Activity"
Jpn. J. Appl. Phys. 51, 117001, database
- 2011
- Li Y, Shinohara R, Iwami K, Ohta Y, and Umeda N
"Observation of Mitochondrial Activity based on Time and Spatial pH
Variation Measured by Near-Field Fluorescent Ratiometry"
Science China, Physics, Mechanics and Astronomy 54, 2225-2229, database
Kanazashi Y, Li Y, Onojima T, Iwami K, Ohta Y, and Umeda N
"Two-photon fluorescence near-field pH measurement for mitochondria
activity"
Proceedings of SPIE. 8105, 81050E, database
- 2010
- Li Y, Shinohara R, Iwami K, Ohta Y, and Umeda N
"Dual Wavelength Fluorescent Ratiometric pH Measurement by Scanning
Near-Field Optical Microscopy"
Proceedings of SPIE. 7544, 754419, database
- 2009
- Fujita C, Ichikawa F, Teratani Y, Murakami G, Okada T, Shinohara M, Kawato S, and Ohta Y
"Direct effects of corticosterone on ATP production by mitochondria
from immortalized hypothalamic GT1-7 neurons"
J. Steroid Biochem. Mol. Biol. 117, 50-55, database
Tazawa H, Fujita C, Machida K, Osada H, and Ohta Y
"Involvement of cyclophilin D in mitochondrial permeability transition
in intact cells"
Arch. Biochem. Biophys. 481, 59-64, database
Fujita C, Matsunomoto Y, and Ohta Y
"Imaging of Mitochondrial Permeability Transition in Cells"
The Journal of Physiological Sciences 59 Suppl.1, 348
Ohta Y, and Morikawa D
"Single Mitochondrion Imaging of Permeability Transition and Swelling"
The Journal of Physiological Sciences 59 Suppl.1, 347
- 2006
- Uechi Y, Yoshioka H, Morikawa D, and Ohta Y
"Stability of membrane potential in heart mitochondria: single mitochondrion
imaging"
Biochem. Biophys. Res. Commun. 344, 1094-1101, database
Machida K, Ohta Y, and Osada H
"Suppression of apoptosis by cyclophilin D via stabilization of hexokinase
II mitochondrial binding in cancer cells"
J. Biol. Chem. 281, 14314-14320, database
Ishii H, Shibuya K, Ohta Y, Mukai H, Uchino S, Takata N, Rose J. A., and
Kawato S
"Enhancement of nitric oxide production by association of nitric oxide
synthase with N-methyl-d-aspartate receptors via postsynaptic density 95
in genetically engineered Chinese hamster ovary cells: real-time fluorescence
imaging using nitric oxide sensitive dye"
Journal of Neurochemistry 96, 1531-1539, database
- 2005
- Higuchi Y, Miura T, Kajimoto T, and Ohta Y
"Effects of disialoganglioside GD3 on the mitochondrial membrane potential"
FEBS Letters 579, 3009-3013, database
Hattori T, Watanabe K, Uechi Y, Yoshioka H, and Ohta Y
"Repetitive transient depolarizations of the inner mitochondrial membrane
induced by proton pumping"
Biophys J. 88, 2340-2349, database
- 2004
- Chiyo T, Yamazaki T, Aoshika K, Kominami S, and Ohta Y
"Evaluation of Corticosterone Effects on Bovine Adrenocotrical Cells
with Single Cell Imaging"
Bioimages 12, 42
- 2003
- Sekiguchi M, Chiyo T, Kawahara M, and Ohta Y
"Effects of progesterone on intracellular Ca2+ levels of immortalized
hypothalamic neurons (GT1-7): Fluorescence Imaging Study”
Bioimages 11, 67-73, database
Chiyo T, Yamazaki T, Aoshika K, Kominami S, and Ohta Y
"Corticosterone Enhances ACTH-induced Calcium Signals in Bovine Adrenocortical
Cells"
Endocrinology 144, 3376-3381, database
- 2002
- Nakayama S, Sakuyama T, Mitaku S, and Ohta Y
“Fluorescence imaging of metabolic responses in single mitochondria”
Biochem. Biophys. Res. Commun. 290, 23-28, database
- 2001
- Yamada M, Ohta Y, Bachmanova G I, Archakov A I, Hatta I, and Kawato S
“Effect of Microsome-Liposome Fusion on the Rotational Mobility of Cytochrome
P450IIB4 in Rabbit Liver Microsomes”
J. Inorg. Biochem. 83, 261-268, database
- 2000
- Homma R, Kimoto T, Niimura Y, Krivosheev A, Hara T, Ohta Y, and Kawato
S
“Real-time fluorescence analysis on molecular mechanisms for regulation
of cytochrome P450scc activity upon steroidogenic stimulation in adrenocortical
cells"
J. Inorg. Biochem., 82, 171-180, database
Hoolahan M, Matsuyama A, Kawato S, and Ohta Y
“Calcium ion enhances the production of NAD(P)H and pregnenolone in bovine
adrenocortical mitochondria.”
Molecular Steroidogenesis (Edited by M.Okamoto, Y. Ishimura, and H. Nawata),
pp 285-286, Universal Academy Press Inc, Tokyo
- 1999
- Yamada M, Ohta Y, Sakaki T, Yabusaki Y, Ohkawa H, and Kawato S
"Dynamic mobility of genetically expressed fusion protein between
cytochrome P4501A1 and NADPH-cytochrome P450 reductase in yeast microsomes"
Biochemistry 38, 9465-9470, database
Suzuki-Tomii K, Ohta Y, Kawato S, and Mitaku S
“Comparative Experiments of Protein Denaturation for Studying Structural
Difference of Homologous membrane Proteins: P450scc and P45011β"
Jpn. J. Appl. Phys. 38, 298-301
- 1998
- Yamazaki T, Kimoto T, Higuchi K, Ohta Y, Kawato S, and Kominami S
"Calcium Ion as a Second Messenger for O-Nitrophenylsulfenyl-Adrenocorticotropin
(ACTH) and ACTH in Bovine Adrenal Steroidogenesis"
Endocrinology, 139, 4765-4771, database
- 1997
- Kimoto T, Ohta Y, and Kawato S
"Heterogeneous Populations of Adrenal Fasciculata Cells Examined with
Ca2+ Signaling and Immunostaining: Single Cell Imaging”
Bioimages, 5, 133-142, database
Kimoto T, Asou H, Ohta Y, Mukai H, Chernogolov A A, and Kawato S
"Digital Fluorescence Imaging of Elementary Steps of Neurosteroid
Synthesis in Rat Brain Glial Cells"
J. Pharmaceutical and Biomedical Analysis, 15, 1231-1240, database
- 1996
- Kimoto T, Ohta Y, and Kawato S
"Adrenocorticotropin Induces Calcium Oscillations in Adrenal Fasciculata
Cells: Single Cell Imaging"
Biochem. Biophys. Res. Commun. 221, 25-30, database
- 1995
- Yamada M, Ohta Y, Bachmanova G I, Nishimoto Y, Archakov A I, and Kawato
S
"Dynamic Interactions of Rabbit Liver Cytochrome P450IA2 and P450IIB4
with Cytochrome b5 and NADPH-Cytochrome P450 Reductase in Proteoliposomes"
Biochemistry 34, 10113-10119, database
- 1994
- Ohta Y, Sakaki T, Yabusaki Y, Ohkawa H, and Kawato S
"Rotation and Membrane Topology of Genetically Expressed Methylcholanthrene-inducible
Cytochrome P-450IA1 Lacking the N-terminal Hydrophobic Segment in Yeast
Microsomes"
J. Biol. Chem. 269, 15597-15600, database
Ohta Y, Yamada M, and Kawato S
"Dynamic Topology and Electron Transfer Interactions of Microsomal
Cytochrome P450 in Liver and Adrenal Cortex: Protein Rotation Study"
Cytochrome P450: Biochemistry, Biophysics and Molecular Biology (Edited
by M.C. Lechner), pp.889-892, John Libbey, Eurotext, Paris
- 1993
- Kominami S, Tagashira H,Ohta Y, Yamada M, Kawato S, and Takemori S
"Membrane Topology of Bovine Adrenocortical Cytochrome P-450C21: Structural
Studies by Trypsin Digestion in Vesicle Membranes"
Biochemistry 32, 12935-12940, database
- 1992
- Ohta Y, Kawato S, Tagashira H, Takemori S, and Kominami S
"Dynamic Structures of Adrenocortical Cytochrome P-450 in Proteoliposomes
and Microsomes: Protein Rotation Study"
Biochemistry 31, 12680-12687, database
Tanji K, Ohta Y, Kawato S, Natori S, and Sekimizu K
"Decrease by Phychotropic Drugs and Local Anesthetics of Membrane
Fluidity Measured by Fluorescence Anisotropy in Escherichia coli"
J. Pharm. Pharmacol. 44, 1036-1037, database
Ohta Y, and Kawato S
"Dynamic Membrane Topology of Microsomal Cytochrome P450"
J. Basic & Clinical Physiology and Pharmacology 3 suppl. 119
Ohta Y, Hieda H, and Kawato S
“Electron Transfer Protein-Protein Interactions in
Bovine Adrenocortical Mitochondria and Phospholipid Vesicles”
J. Basic & Clinical Physiology and Pharmacology 3
suppl. 216
- 1991
- Iwase T, Sakaki T, Yabusaki Y, Ohkawa H, Ohta Y, and Kawato S
"Rotation and Protein-Protein Interactions of Genetically Expressed
Cytochrome P-450 in Yeast Microsomes"
Biochemistry 30, 8347-8351, database
Etter H, Richter C, Ohta Y, Winterhalter K H, Sasabe H, and Kawato S
"Rotation and Interactions with Epoxide Hydrase of Cytochrome P-450
in Proteoliposomes"
J. Biol. Chem. 266, 18600-18605, database
Ohta Y, Yanagibashi K, Hara T, Kawamura M, and Kawato S
"Protein Rotation Study of Cytochrome P-450 in Submitochondrial Particles:
Effect of KCl and Intermolecular Interactions with Redox Partners"
J. Biochem. 109, 594-599, database
Ohta Y, and Kawato S
"Electron Transfer Interactions of Cytochrome P-450 in Adrenocortical
Mitochondria"
Cytochrome P-450: Biochemistry and Biophysics (Edited by A.I. Archakov
and G.I. Bachmanova) pp 300-302, INCO-TNC, Joint Stock Company, Russia
Kawato S, and Ohta Y
"Electron Transfer Interactions of Cytochrome
P-450 in Liver and Adrenal Cortex Membranes"
Cytochrome P-450: Biochemistry and Biophysics (Edited by A.I. Archakov
and G.I. Bachmanova) pp 222-227, INCO-TNC, Joint Stock Company, Russia
- 1990
- Komura S, Ohta Y, and Kawato S.
"A Theory of Optical Anisotropy Decay in Membranes"
J. Phys. Soc. Japan 59, 2584-2595, database
Ohta Y, Mitani F, Ishimura Y, Yanagibashi K, Kawamura M, and Kawato S
"Conversion of Cholesterol to Pregnenolone Mobilizes Cytochrome P-450
in the Inner Membrane of Adrenocortical Mitochondria: Protein Rotation
Study"
J. Biochem. 107, 97-104, database
