Research

Organic electrolysis

We have been developing organic reactions induced by electron transfer on electrode (Electro-organic reaction) and we aim to apply the reactions to synthesis biologically active agent and explore medicinal products.
In particular, we focus on carbon-carbon forming reactions specific to lithium perchlorate nitromethane electrolyte solution¹.
These reactions have been applied to the electron-transfer probe², fluorescent probe³, synthesis of bio-molecular relevant compounds⁴, on the basis of reaction mechanism.

References
1) J. Am. Chem. Soc., 2001, 123, 11314-11315. Angew. Chem. Int. Ed., 2006, 45, 1461-1463. Org. Lett., 2007, 9, 4347-4350. Org. Lett. 2009, 11, 1033-1035.
2) J. Org. Chem. 2011, 76, 3470–3476. J. Org. Chem. 2013, 78, 2626-2638.
3) Chem. Eur. J. 2012, 18, 6284-6288.
4) Chem. Commun. 2013, 49, 6525-6527. Eur. J. Org. Chem. 2014, 1371-1375. Org. Lett. 2014, 16, 6404-6407.

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